AtaGenix

Anti Bcl2 polyclonal antibody

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ATP012
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product nameicon
Anti Bcl2 polyclonal antibody
catalog No.icon
ATP012
Categoryicon
Primary antibody
Hosticon
Rabbit
Species specificityicon
Human,other species was not test
Tested applicationsicon
ICC:1:50~200,IHC:1:50~100
Clonalityicon
Polyclonal
Conjugationicon
Unconjugated
Immunogenicon
Recombinant protein of human Bcl2(Met1-Asp211).
Alternative Namesicon
Apoptosis regulator Bcl 2,Apoptosis regulator Bcl-2,Apoptosis regulator Bcl2,AW986256,B cell CLL/lymphoma 2,B cell leukemia/lymphoma 2,Bcl-2,
Bcl2,BCL,C430015F12Rik,D630044D05Rik,D830018M01Rik,Leukemia/lymphoma,B-cell,Oncogene B-cell leukemia 2,PPP1R50,Protein phosphatase 1 regulatory subunit 50,Protein phosphatase 1,regulatory subunit 50
Uniprot IDicon
P10415
Formicon
Liquid
Buffericon
PBS,pH7.4,containing 0.05% proclin300,50% glycerol.
Storageicon
Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 4°C for frequent use.Store at -20 to -80 °C for twelve months from the date of receipt.
Concentrationicon
0.55mg/ml
Isotypeicon
IgG
MWicon
26kDa
Purityicon
Antigen affinity purification
ICC,IHC
    PubMed:17418785;PMID: 18570871;PMID: 8183370
    BCL2 belongs to the Bcl-2 family. It suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. BCL2 regulates cell death by controlling the mitochondrial membrane permeability (PMID: 10365962). It appears to function in a feedback loop system with caspases. BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (PMID: 10444588). This antibody is not suitable for rat and mouse species.

    Guarantee and Disclaimer:

    After receiving the product, if finds that the product is mismatched, damaged or missing components, please keep the original package and submit the objection to the company by mail within seven working days. Failure to file an objection within the time limit is considered qualified.

    When the buyer keeps the product, it should be kept in accordance with the storage conditions shown in the product label and the manual. If the product quality is caused by improper storage, it will not be guaranteed.

    When the buyer tests the product, they should be submitted by the beginning of use when found the quality issue, rather than when the product was used or used up, in order to prepare our products for recycling and confirm the quality of the products. If it is the quality problem, our company is responsible for exchange or return. In the event of a claim, our company will compensate the discretion within the scope of the product price limit and will not accept any part of the value of the product itself. Since the date of receipt, the product has not been reflected for more than three months and should not be returned.

    The products provided by our company are for research use only and should not be used for clinical diagnosis or treatment. If a unit or individual changes the use of our products without authorization, we will not bear any responsibility.