Immunoassay is an important means of clinical diagnosis and treatment (e.g. virus, hormone, tumor marker and other types of detection). Chemiluminescence immunoassay is the latest immunoassay technology developed after radioimmunoassay, fluorescence immunoassay and enzyme immunoassay, which has the advantages of high sensitivity, no radioactive contamination, wide detection range and good stability of markers, and it is the main form of development of immunoassay field.

Chemiluminescence immunoassay includes two parts: immune reaction and chemiluminescence. Using bio-immunity technology to realize the specific combination of the substance to be tested, the luminescent marker and the target substance, so that it luminesces in an alkaline environment, and the light energy released corresponds monotonically with the concentration of the substance to be tested, so that the concentration of the substance to be tested can be obtained indirectly through the measurement of the light energy. At present, the popular target substances are immunomagnetic particles, i.e., ferrite particles encapsulated with antibodies or antigens, which can be bound by a magnetic field to facilitate the separation of substances; luminescent markers are obtained by labeling a chemiluminescent agent (acridinium ester or isoluminol) on an antibody.

AtaGenix provides development technical services for chemiluminescent monoclonal antibody pairs, using acridine ester direct luminescence system, chemiluminescent reagents in the luminescence immunoassay process without enzyme catalytic effect, directly involved in the luminescence reaction. They have the characteristic group of luminescence in their chemical structure, and can directly label antigen or antibody.

Instrument Performance Parameters

Testing speed: 180 tests/H; Detection principle: magnetic particles direct chemiluminescence; Marker: acridine ester; Testing mode: random, batch, emergency; Sample position: 40; Reagent position: 9; Carrying contamination rate: ≤ 10-5; Precision: CV ≤ 3%.

1.5 protein expression platforms to promote antigen preparation

2.Experience in independent research and development of chemiluminescence reagent kits

3. Customized experimental solutions

4. Direct chemiluminescence is fast

5. Good reagent stability