Recombinant 2019-nCoV Nucleocapsid protein, His Tag (B.1.1.529/Omicron)

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Summaryicon
Product name
Recombinant 2019-nCoV Nucleocapsid protein, His Tag (B.1.1.529/Omicron)
Catalog#
ATYP10374COV
description
A DNA sequence encoding the SARS-CoV-2 Nucleocapsid (YP_009724397.2, with mutations P13L, ERS31-33 deletion, R203K, G204R) (Met1-Ala419) was expressed with a polyhistidine tag at the N-terminus. The mutations were identified in the SARS-CoV-2 variant (known as variant B.1.1.529) which emerged in the South Africa.
Expression system
E.coli
Accession #
YP_009724397.2
Purity
>90% as determined by SDS-PAGE
Endotoxin level
Please contact with the lab for this information
Formulation
Lyophilized. Lyophilized from PBS pH7.5,0.02%NLS,1mM EDTA, 4%trehalose,1% mannitol
Shipping
In general, proteins are shipped out with blue ice unless customers require
otherwise
Stability &Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Reconstitution
Please refer to the instraction in the hard copy of COA.
Application
Immunogen
Backgroundicon
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. The coronavirus N protein is required for coronavirus RNA synthesis and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is the most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to the formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of the N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Product performanceicon
Form
liquid
MW
46.31 kDa

Guarantee and Disclaimer:

After receiving the product, if finds that the product is mismatched, damaged or missing components, please keep the original package and submit the objection to the company by mail within seven working days. Failure to file an objection within the time limit is considered qualified.

When the buyer keeps the product, it should be kept in accordance with the storage conditions shown in the product label and the manual. If the product quality is caused by improper storage, it will not be guaranteed.

When the buyer tests the product, they should be submitted by the beginning of use when found the quality issue, rather than when the product was used or used up, in order to prepare our products for recycling and confirm the quality of the products. If it is the quality problem, our company is responsible for exchange or return. In the event of a claim, our company will compensate the discretion within the scope of the product price limit and will not accept any part of the value of the product itself. Since the date of receipt, the product has not been reflected for more than three months and should not be returned.

The products provided by our company are for research use only and should not be used for clinical diagnosis or treatment. If a unit or individual changes the use of our products without authorization, we will not bear any responsibility.