AtaGenix

Hot search： CD47 │ IL6 │ PD-L1 │ CTLA-4 │ TIGIT
Current Site： Product Center / 2019-nCoV products / 2019-nCoV Antibody / Anti TMPRSS2 polyclonal antibody

Anti TMPRSS2 polyclonal antibody

  • 1
  • 2
  • 3
  • 4
ATP226
-
+
Spot
Inquiry
  • Product Details
  • References
  • How to order
  • Instructions
Summaryicon
description
Produced in rabbits immunized with purified,Recombinant Human TMPRSS2 protein
Accession #
O15393
Alternative names
PP9284, PRSS10, Serine protease 10, TMPRSS2
Stability &Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -99 °C for twelve months from the date of receipt.
Spcificity
Recognizes Human TMPRSS2 protein
Isotype
IgG
Host
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Species reactivity
Human,other species was not test
Tested applications
WB,IHC
Immunogen
Recombinant Human TMPRSS2 protein
Backgroundicon
TMPRSS2, also named as PRSS10, is a type II transmembrane serine protease which is highly expressed by the epithelium of the human prostate gland. TMPRSS2 may contribute to prostate tumour metastasis via the activation of PAR-2. TMPRSS2 is a Serine protease that proteolytically cleaves and activates the viral spike glycoproteins which facilitate virus-cell membrane fusions. TMPRSS2 as a host cell factor that is critical for spread of several clinically relevant viruses, including influenza A viruses and coronaviruses.SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming. The initial spike protein priming by TMPRSS2 is essential for entry and viral spread of SARS-CoV-2 through interaction with the ACE2 receptor.Camostat mesylate, an inhibitor of TMPRSS2, can block SARS-CoV-2 infection of lung cells.The MW of TMPRSS2 is about 65-70 kDa. It can be cleaved in to some chains with MW 54 kDa, 31 kDa and 26 kDa
Product performanceicon
Form
Liquid
Buffer
PBS,pH7.4,containing 0.05% proclin300,50% glycerol.
Concentration
0.5mg/ml
MW
54kDa
Applicationicon
Dilution Range
WB:1:2000-1:8000,IHC:1:200-1:400
Tested Pictureicon
    Noteicon
    For research use only.
    PMID: 23468491, 30626688;PMID: 32142651, 30626688 ;PMID: 32142651;PMID: 25734995, 20382709, 26018085

    Guarantee and Disclaimer:

    After receiving the product, if finds that the product is mismatched, damaged or missing components, please keep the original package and submit the objection to the company by mail within seven working days. Failure to file an objection within the time limit is considered qualified.

    When the buyer keeps the product, it should be kept in accordance with the storage conditions shown in the product label and the manual. If the product quality is caused by improper storage, it will not be guaranteed.

    When the buyer tests the product, they should be submitted by the beginning of use when found the quality issue, rather than when the product was used or used up, in order to prepare our products for recycling and confirm the quality of the products. If it is the quality problem, our company is responsible for exchange or return. In the event of a claim, our company will compensate the discretion within the scope of the product price limit and will not accept any part of the value of the product itself. Since the date of receipt, the product has not been reflected for more than three months and should not be returned.

    The products provided by our company are for research use only and should not be used for clinical diagnosis or treatment. If a unit or individual changes the use of our products without authorization, we will not bear any responsibility.

    AtaGenix
    Copyright © 2024 Lawyer Theme All Rights Reserved
    Site map | Contact us | Join us