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Anti CD147 polyclonal antibody

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Summaryicon
description
Produced in rabbits immunized with purified,Recombinant Human CD147 protein
Accession #
P35613-2
Alternative names
Collagenase stimulatory factor,OK blood group antigen,Leukocyte activation antigen M6,Tumor cell-derived collagenase stimulatory factor,Basigin,Extracellular matrix metalloproteinase inducer,CD147,TCSF,EMMPRIN,5F7,BSG
Stability &Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Spcificity
Recognizes Human CD147 protein
Isotype
IgG
Host
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Species reactivity
Human,other species was not test
Tested applications
WB,ICC,IHC
Immunogen
Recombinant protein of human CD147(Ala22-Ala207).
Backgroundicon
BSG, also named as 5F7, Basigin, EMMPRIN, TCSF and CD147, plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS).CD147 may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. It seems to be a receptor for oligomannosidic glycans. CD147 is a receptor of CypA, inducing matrix metalloproteinase expression and mediating the degradation of the extracellular matrix, plays an important role in tumorigenesis and invasion in oral cancer. It has been considered as an objective and effective marker to predict invasion and prognosis in various cancers.
Product performanceicon
Form
Liquid
Buffer
PBS,pH7.4,containing 0.05% proclin300,50% glycerol.
Concentration
0.48mg/ml
MW
42kDa
Applicationicon
Dilution Range
WB:1:2000~1:8000,ICC:1:50~200,IHC:1:50~100
Tested Pictureicon
    Noteicon
    For research use only.
    PubMed:21778275;PubMed:22080952;PubMed:26195724;PubMed:28409866

    Guarantee and Disclaimer:

    After receiving the product, if finds that the product is mismatched, damaged or missing components, please keep the original package and submit the objection to the company by mail within seven working days. Failure to file an objection within the time limit is considered qualified.

    When the buyer keeps the product, it should be kept in accordance with the storage conditions shown in the product label and the manual. If the product quality is caused by improper storage, it will not be guaranteed.

    When the buyer tests the product, they should be submitted by the beginning of use when found the quality issue, rather than when the product was used or used up, in order to prepare our products for recycling and confirm the quality of the products. If it is the quality problem, our company is responsible for exchange or return. In the event of a claim, our company will compensate the discretion within the scope of the product price limit and will not accept any part of the value of the product itself. Since the date of receipt, the product has not been reflected for more than three months and should not be returned.

    The products provided by our company are for research use only and should not be used for clinical diagnosis or treatment. If a unit or individual changes the use of our products without authorization, we will not bear any responsibility.

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