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Recombinant Human CD147 protein

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ATAP00046
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Summaryicon
Product name
Recombinant Human CD147 protein
Catalog#
ATAP00046
description
Recombinant Human CD147 is produced by E.coli expression system and the target gene encoding Ala22-Ala207 is expressed with His Tag
Expression system
E.coli
Species
Homo sapiens (Human)
Accession #
P35613
Alternative names
5F7 Protein, Human; Basigin Protein, Human; CD147 Protein, Human; EMMPRIN Protein, Human; M6 Protein, Human; OK Protein, Human; TCSF Protein, Human
Predicted Molecular Mass
22.59 kDa
Purity
>90% as determined by SDS-PAGE
Endotoxin level
Please contact with the lab for this information
Formulation
Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
Shipping
In general, proteins are shipped out with blue ice unless customers require otherwise.
Stability &Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Reconstitution
Please refer to the instraction in the hard copy of COA.
Application
Immunogen
SDS-PAGE imageicon
    Bioactivityicon
      Backgroundicon
      CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers.
      Noteicon
      For research use only.

      Guarantee and Disclaimer:

      After receiving the product, if finds that the product is mismatched, damaged or missing components, please keep the original package and submit the objection to the company by mail within seven working days. Failure to file an objection within the time limit is considered qualified.

      When the buyer keeps the product, it should be kept in accordance with the storage conditions shown in the product label and the manual. If the product quality is caused by improper storage, it will not be guaranteed.

      When the buyer tests the product, they should be submitted by the beginning of use when found the quality issue, rather than when the product was used or used up, in order to prepare our products for recycling and confirm the quality of the products. If it is the quality problem, our company is responsible for exchange or return. In the event of a claim, our company will compensate the discretion within the scope of the product price limit and will not accept any part of the value of the product itself. Since the date of receipt, the product has not been reflected for more than three months and should not be returned.

      The products provided by our company are for research use only and should not be used for clinical diagnosis or treatment. If a unit or individual changes the use of our products without authorization, we will not bear any responsibility.

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