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Anti 2019-nCoV S1 Protein polyclonal antibody

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Summaryicon
Product name
Anti 2019-nCoV S1 Protein polyclonal antibody
Catalog#
ATP246
description

Produced in rat immunized with purified,Recombinant SARS-CoV-2 S1 Protein

Accession #
P0DTC2
Alternative names
Spike glycoprotein,E2,Peplomer protein,Spike protein S1,S
Stability &Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -91 °C for twelve months from the date of receipt.
Spcificity
Recognizes SARS-CoV-2 S1 Protein
Isotype
IgG
Host
Rat
Clonality
Polyclonal
Conjugation
Unconjugate
Species reactivity
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2)
Tested applications
Elisa
Immunogen
Recombinant SARS-CoV-2 S1 Protein(Val16-Gln677)
Backgroundicon
Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. Binding to human ACE2 receptor and internalization of the virus into the endosomes of the host cell induces conformational changes in the Spike glycoprotein. Uses also human TMPRSS2 for priming in human lung cells which is an essential step for viral entry. Can be alternatively processed by host furin . Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.
Product performanceicon
Form
Liquid
Buffer
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
Concentration
0.61mg/ml
MW
141kDa
Applicationicon
Dilution Range
Elisa:1:4000~1:8000
Tested Pictureicon
    Noteicon
    For research use only.
    PubMed:32142651, PubMed:32075877, PubMed:32155444, PubMed:32362314

    Guarantee and Disclaimer:

    After receiving the product, if finds that the product is mismatched, damaged or missing components, please keep the original package and submit the objection to the company by mail within seven working days. Failure to file an objection within the time limit is considered qualified.

    When the buyer keeps the product, it should be kept in accordance with the storage conditions shown in the product label and the manual. If the product quality is caused by improper storage, it will not be guaranteed.

    When the buyer tests the product, they should be submitted by the beginning of use when found the quality issue, rather than when the product was used or used up, in order to prepare our products for recycling and confirm the quality of the products. If it is the quality problem, our company is responsible for exchange or return. In the event of a claim, our company will compensate the discretion within the scope of the product price limit and will not accept any part of the value of the product itself. Since the date of receipt, the product has not been reflected for more than three months and should not be returned.

    The products provided by our company are for research use only and should not be used for clinical diagnosis or treatment. If a unit or individual changes the use of our products without authorization, we will not bear any responsibility.

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