AtaGenix

Recombinant 2019-nCoV E protein

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ATEP02466COV
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Summaryicon
Catalog#
ATEP02466COV
description
Recombinant SARS-CoV-2 E protein is produced by E.coli expression system and the target gene encoding Met1-Val75 is expressed with N-His-sumo Tag
Expression system
E.coli
Species
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Accession #
QHD43418.1
Alternative names
2019-nCoV E protein,2019-nCoV sM protein
Predicted Molecular Mass
21.04kDa
Purity
>90% as determined by SDS-PAGE
Endotoxin level
Please contact with the lab for this information
Formulation
Supplied as solution form in PBS, pH7.4/ Supplied as lyophilized from PBS, pH7.4
Shipping
In general, proteins are shipped out with blue ice unless customers require otherwise.
Stability &Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Reconstitution
Reconstitute in sterile water for a stock solution.
Application
Immunogen
SDS-PAGE imageicon
    Backgroundicon
    Coronavirus envelope (E) proteins are short (100 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.
    Product performanceicon
    Form
    Recombinant 2019-nCoV E protein
    Noteicon
    For research use only.

    Guarantee and Disclaimer:

    After receiving the product, if finds that the product is mismatched, damaged or missing components, please keep the original package and submit the objection to the company by mail within seven working days. Failure to file an objection within the time limit is considered qualified.

    When the buyer keeps the product, it should be kept in accordance with the storage conditions shown in the product label and the manual. If the product quality is caused by improper storage, it will not be guaranteed.

    When the buyer tests the product, they should be submitted by the beginning of use when found the quality issue, rather than when the product was used or used up, in order to prepare our products for recycling and confirm the quality of the products. If it is the quality problem, our company is responsible for exchange or return. In the event of a claim, our company will compensate the discretion within the scope of the product price limit and will not accept any part of the value of the product itself. Since the date of receipt, the product has not been reflected for more than three months and should not be returned.

    The products provided by our company are for research use only and should not be used for clinical diagnosis or treatment. If a unit or individual changes the use of our products without authorization, we will not bear any responsibility.