AtaGenix

Anti Vimentin polyclonal antibody

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ATP006
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product nameicon
Anti Vimentin polyclonal antibody
catalog No.icon
ATP006
Categoryicon
Primary antibody
Hosticon
Rabbit
Species specificityicon
Human,other species was not test
Tested applicationsicon
WB:1:2000~1:8000,ICC:1:50~200,IHC:1:50~100
Clonalityicon
Polyclonal
Conjugationicon
Unconjugated
Immunogenicon
Recombinant protein of human Vimentin(Met1-Glu466).
Alternative Namesicon
CTRCT30,Epididymis luminal protein 113,FLJ36605,HEL113,VIM,VIME,Vimentin
Uniprot IDicon
P08670
Formicon
Liquid
Buffericon
PBS,pH7.4,containing 0.05% proclin300,50% glycerol.
Storageicon
Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 4°C for frequent use.Store at -20 to -80 °C for twelve months from the date of receipt.
Concentrationicon
0.57mg/ml
Isotypeicon
IgG
MWicon
54kDa
Purityicon
Antigen affinity purification
WB,ICC,IHC
    PMID: 21746880 ;PMID: 21465480 ;PMID: 8601315
    Vimentin, also named as VIM, belongs to the intermediate filament family. Vimentin is class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is important for stabilizing the architecture of the cytoplasm. Monocyte-derived macrophages secrete vimentin into the extracellular space in vitro. Secretion of vimentin was enhanced by the proinflammatory cytokine tumor necrosis factor-alpha (TNFA,191160) and inhibited by the antiinflammatory cytokine IL10 (124092), suggesting that vimentin is involved in the immune response. Vimentin has specialized functions that contribute to specific dynamic cellular processes. As a phosphoprotein, 55-60 kDa of vimentin proteins can be observed due to the different phosphorylation level. Isoforms of vimentin (49 kDa and 60 kDa) had also been reported. (PMID: 8640945, 22728585).

    Guarantee and Disclaimer:

    After receiving the product, if finds that the product is mismatched, damaged or missing components, please keep the original package and submit the objection to the company by mail within seven working days. Failure to file an objection within the time limit is considered qualified.

    When the buyer keeps the product, it should be kept in accordance with the storage conditions shown in the product label and the manual. If the product quality is caused by improper storage, it will not be guaranteed.

    When the buyer tests the product, they should be submitted by the beginning of use when found the quality issue, rather than when the product was used or used up, in order to prepare our products for recycling and confirm the quality of the products. If it is the quality problem, our company is responsible for exchange or return. In the event of a claim, our company will compensate the discretion within the scope of the product price limit and will not accept any part of the value of the product itself. Since the date of receipt, the product has not been reflected for more than three months and should not be returned.

    The products provided by our company are for research use only and should not be used for clinical diagnosis or treatment. If a unit or individual changes the use of our products without authorization, we will not bear any responsibility.