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Recombinant Human ACE2 protein

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ATMP02469COV
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Summaryicon
Product name
Recombinant Human ACE2 protein
Catalog#
ATMP02469COV
description
Recombinant Human ACE2 is produced by Mammalian cells expression system and the target gene encoding Ser19-Asp615 is expressed with C-His Tag
Expression system
Mammalian cells
Species
Homo sapiens (Human)
Accession #
NP_001358344.1 or Uniprot Q9BYF1
Alternative names
ACE-related carboxypeptidase,Angiotensin-converting enzyme homolog,Metalloprotease MPROT15
Predicted Molecular Mass
71.54kDa
Actual Molecular Mass
90-100kDa
Purity
>90% as determined by SDS-PAGE
Endotoxin level
Please contact with the lab for this information.
Formulation
Supplied as lyophilized from PBS pH7.4，1mM EDTA, 4%trehalose，1% mannitol.
Shipping
In general, proteins are shipped out with blue ice unless customers require otherwise.
Stability &Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week . Store at -20 to -80 °C for twelve months from the date of receipt.
Reconstitution
Reconstitute in sterile water for a stock solution.
Application
Immunogen
SDS-PAGE imageicon
    Backgroundicon
    Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
    Noteicon
    For research use only.

    Guarantee and Disclaimer:

    After receiving the product, if finds that the product is mismatched, damaged or missing components, please keep the original package and submit the objection to the company by mail within seven working days. Failure to file an objection within the time limit is considered qualified.

    When the buyer keeps the product, it should be kept in accordance with the storage conditions shown in the product label and the manual. If the product quality is caused by improper storage, it will not be guaranteed.

    When the buyer tests the product, they should be submitted by the beginning of use when found the quality issue, rather than when the product was used or used up, in order to prepare our products for recycling and confirm the quality of the products. If it is the quality problem, our company is responsible for exchange or return. In the event of a claim, our company will compensate the discretion within the scope of the product price limit and will not accept any part of the value of the product itself. Since the date of receipt, the product has not been reflected for more than three months and should not be returned.

    The products provided by our company are for research use only and should not be used for clinical diagnosis or treatment. If a unit or individual changes the use of our products without authorization, we will not bear any responsibility.

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