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Recombinant 2019-nCoV NSP8

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ATEP02460COV
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Summaryicon
Product name
Recombinant 2019-nCoV NSP8
Catalog#
ATEP02460COV
description
Recombinant SARS-CoV-2 NSP8 is produced by E.coli expression system and the target gene encoding Ala1-Gln198 is expressed with N-His Tag
Expression system
E.coli
Species
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Accession #
YP_009725304.1
Alternative names
SARS-CoV 2 nsp8
Predicted Molecular Mass
24.18kDa
Actual Molecular Mass
24kDa
Purity
>90% as determined by SDS-PAGE
Endotoxin level
Please contact with the lab for this information.
Formulation
Supplied as solution form in PBS, pH7.4/ Supplied as lyophilized from PBS, pH7.4
Shipping
In general, proteins are shipped out with blue ice unless customers require otherwise.
Stability &Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Reconstitution
Reconstitute in sterile water for a stock solution.
Application
Immunogen
SDS-PAGE imageicon
    Backgroundicon
    Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. Nsp8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that could be involved in producing primers utilized by nsp12 which is normally accepted to be the RdRp for SARS-CoV.
    Product performanceicon
    Form
    Recombinant SARS-CoV-2 (2019-nCoV) NSP8
    Noteicon
    For research use only.

    Guarantee and Disclaimer:

    After receiving the product, if finds that the product is mismatched, damaged or missing components, please keep the original package and submit the objection to the company by mail within seven working days. Failure to file an objection within the time limit is considered qualified.

    When the buyer keeps the product, it should be kept in accordance with the storage conditions shown in the product label and the manual. If the product quality is caused by improper storage, it will not be guaranteed.

    When the buyer tests the product, they should be submitted by the beginning of use when found the quality issue, rather than when the product was used or used up, in order to prepare our products for recycling and confirm the quality of the products. If it is the quality problem, our company is responsible for exchange or return. In the event of a claim, our company will compensate the discretion within the scope of the product price limit and will not accept any part of the value of the product itself. Since the date of receipt, the product has not been reflected for more than three months and should not be returned.

    The products provided by our company are for research use only and should not be used for clinical diagnosis or treatment. If a unit or individual changes the use of our products without authorization, we will not bear any responsibility.

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