AtaGenix

BOB.1 mouse monoclonal antibody

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ATDA00009
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product nameicon
BOB.1 mouse monoclonal antibody
catalog No.icon
ATDA00009
Categoryicon
Primary antibody
Hosticon
Mouse
Species specificityicon
This antibody detects endogenous levels of human BOB.1. Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section
Tested applicationsicon
IHC-p
Clonalityicon
Monoclonal
Immunogenicon
Synthesized peptide derived from human BOB.1.
Alternative Namesicon
POU domain class 2-associating factor 1,B-cell-specific coactivator OBF-1,BOB-1,OCA-B,OCT-binding factor 1
Uniprot IDicon
Q16633
Formicon
Liquid
Buffericon
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storageicon
Stored at -20℃.Avoid repeated freeze-thaw cycles.
Concentrationicon
1 mg/ml
Isotypeicon
IgG2a,Kappa
IHC-p:1:100-1:500
Disease:A chromosomal aberration involving POU2AF1/OBF1 may be a cause of a form of B-cell leukemia.Translocation t(3;11)(q27;q23) with BCL6,function:Transcriptional coactivator that specifically associates with either OCT1 or OCT2.It boosts the OCT1 mediated promoter activity and to a lesser extent,that of OCT2.It has no intrinsic DNA-binding activity.It recognizes the POU domains of OCT1 and OCT2.It is essential for the response of B-cells to antigens and required for the formation of germinal centers.PTM:Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation,similarity:Belongs to the POU2AF1 family,tissue specificity:B-cell specific.

Guarantee and Disclaimer:

After receiving the product, if finds that the product is mismatched, damaged or missing components, please keep the original package and submit the objection to the company by mail within seven working days. Failure to file an objection within the time limit is considered qualified.

When the buyer keeps the product, it should be kept in accordance with the storage conditions shown in the product label and the manual. If the product quality is caused by improper storage, it will not be guaranteed.

When the buyer tests the product, they should be submitted by the beginning of use when found the quality issue, rather than when the product was used or used up, in order to prepare our products for recycling and confirm the quality of the products. If it is the quality problem, our company is responsible for exchange or return. In the event of a claim, our company will compensate the discretion within the scope of the product price limit and will not accept any part of the value of the product itself. Since the date of receipt, the product has not been reflected for more than three months and should not be returned.

The products provided by our company are for research use only and should not be used for clinical diagnosis or treatment. If a unit or individual changes the use of our products without authorization, we will not bear any responsibility.